Intrauterine insemination success rates vary considerably and depend on
- age of the woman
- type of ovarian stimulation used (if any)
- duration of infertility
- cause of infertility
- number and quality of motile sperm
- other factors
Success rates for IUI in women over 35 drop off, and for women over 40 they are much lower. For this reason, we are more aggressive in “older” women.
The rates are slightly higher for women that do not ovulate on their own (anovulation) that are stimulated to ovulate with medication and then inseminated. The sole cause of their infertility is likely to be the ovulation problem – which is hopefully overcome with the drugs.
For a couple with unexplained infertility, female age under 35, trying for 2 years, and normal sperm – we would generally expect about
- 8% chance per month of conceiving with artificial insemination and Clomephine citrate
- 18% chance per month of conceiving with injectable FSH medication (e.g. Follistim, Gonal-F, or Menopur)
- 68% chance of conceiving with one cycle (month) of IVF treatment (at our center – success rates vary greatly between clinics)
How many infertility treatment cycles should be done with insemination?
Most pregnancies resulting from insemination with the male partner’s sperm occur in the first 3 attempts. The chances for success per month drop off after about 3 attempts and drop considerably more after about 4-5 unsuccessful attempts. Therefore, IUI treatment is usually recommended for a maximum of about 3 or 4 tries.